CD96 anticorps
Aperçu rapide pour CD96 anticorps (ABIN1106624)
Antigène
Voir toutes CD96 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This Monoclonal antibody NK92.39 reacts with CD96, also known as T cell-activated increased late expression (Tactile).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Protein G Chromatography
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 2-8 °C.
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- CD96
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Autre désignation
- CD96
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Sujet
- CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR or CD155). Furthermore CD96 stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. This means NK cells have due to the receptor CD96 a dual receptor system that recognizes nectins and nectin-like molecules on target cells and mediates NK cells adhesion and triggering of effector functions. As PVR is highly expressed in certain tumors, this receptor system may be critical for NK cell recognition of tumors.Synonyms: Cell surface antigen CD96, T cell-activated increased late expression protein, T-cell surface protein tactile, TACTILE
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ID gène
- 10225
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NCBI Accession
- NP_005807
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UniProt
- P40200
Antigène
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